Buy 5F-AKB48 for sale online from USA vendor

Table of Contents

1. Introduction
2. Chemistry
3. Pharmacology
4. Physical Effects
5. Cognitive Effects
6. Toxicity and Harm Potential
7. Legal Status

Introduction

5F-AKB48, also recognized as 5F-APINACA and AKB-48F, belongs to the synthetic cannabinoid family, specifically classified under the indazolecarboxamide class. This compound demonstrates potent agonistic properties towards the CB1 and CB2 cannabinoid receptors, as evidenced by scientific studies.

Investigative Literature

Numerous scientific inquiries have delved into the properties and effects of 5F-AKB48, shedding light on its pharmacological characteristics. Initially identified in South Korea, this synthetic cannabinoid has made its way into the market, often sold as a grey area research chemical through online vendors.

Subjective Effects

Reports on the subjective effects of 5F-AKB48 suggest similarities to cannabis, albeit with a shorter duration and a notable emphasis on intense physical sensations.

Route of Administration

Typically, cannabinoids are either smoked or vaporized to achieve rapid onset and offset of effects. However, 5F-AKB48 demonstrates oral activity when dissolved in lipids, potentially extending its duration of action significantly. Unlike water, this compound is insoluble, but it dissolves in ethanol and lipids.

Safety Concerns

It's crucial to highlight that unlike natural cannabis, chronic abuse of synthetic cannabinoids such as 5F-AKB48 has been linked to severe injuries, fatalities, and heightened toxicity. Hence, the consumption of this substance for prolonged periods or in excessive doses is strongly discouraged.

Understanding 5F-AKB48: Chemistry and Pharmacology

Chemistry

5F-AKB48, chemically known as N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is categorized as a synthetic indazolecarboxamide due to its composition featuring a substituted indazole group. This compound's structure includes an indazole moiety substituted at R1 with a fluoropentyl chain, a trait shared with 5F-PB-22. Additionally, the indazole bears a substitution at R3 with a carboxamide group. Notably, this carboxamide group is N-substituted at its terminal amine group with an adamantane group, comprising four fused cyclohexane rings in a unique arrangement known as a diamondoid. 5F-AKB48 serves as an analog of STS-135, wherein the core indole structure is replaced with an indazole base.

Pharmacology

While formal studies on 5F-AKB48 are lacking, structural analysis suggests similarities in binding profiles to other cannabinoids and alignment with many in vivo properties of Δ9-THC. However, the precise mechanisms underlying these interactions and their manifestation in the cannabinoid high remain obscure.

Subjective Effects

Disclaimer: The subjective effects outlined below reference the Subjective Effect Index (SEI), derived from anecdotal user reports and personal analyses of PsychonautWiki contributors. Consequently, they should be interpreted with caution.

It's essential to note that these effects may not manifest predictably or consistently, with higher doses being more likely to induce the full range of effects. Furthermore, adverse effects, including addiction, severe injury, or fatality, become increasingly probable with higher doses.

Dosage:

• Threshold: 0.5 mg
• Light: 0.5 - 1 mg
• Common: 1 - 2 mg
• Strong: 2 - 4 mg
• Heavy: 4 mg +

These dosage guidelines serve as reference points for understanding the potential effects of 5F-AKB48, although individual responses may vary.

Understanding 5F-AKB48: Physical Effects

Spontaneous Physical Sensations

The "body high" induced by 5F-AKB48 is characterized by a sharp, uncomfortable, all-encompassing, and electric tingling sensation that spreads across the body following ingestion. This sensation persists consistently, escalating rapidly upon onset, reaching its peak, and then promptly subsiding.

Motor Control Loss

5F-AKB48 prompts a partial to moderate suppression of motor control, the severity of which escalates proportionally with dosage. However, it seldom leads to complete incapacitation, allowing individuals to maintain basic movements and walk, albeit with difficulty.

Appetite Enhancement

Similar to numerous other cannabinoids, 5F-AKB48 triggers an increase in appetite, colloquially referred to as "the munchies" in American and British culture. Clinical studies and survey data have evidenced cannabis's ability to enhance food enjoyment and stimulate interest in food. This effect is attributed to the activation of cannabinoid receptors responsible for regulating food intake by endocannabinoids in the hypothalamus.

Pain Relief

Clinical research has established cannabinoids' efficacy in providing pain relief through the agonism of CB1 and CB2 cannabinoid receptors. This analgesic effect extends to synthetic cannabinoid receptor agonists like 5F-AKB48.

Perception Alterations

Users may experience changes in perception, including a sensation of bodily lightness and alterations in the perception of gravity.

Dehydration

A common side effect associated with 5F-AKB48 use is dehydration, colloquially known as "cotton mouth" in American and British culture.

Vasodilation

5F-AKB48 consumption may lead to vasodilation, the widening of blood vessels, which can impact blood pressure regulation and circulation.

Understanding 5F-AKB48: Cognitive Effects

Anxiety and Paranoia

Compared to other cannabinoids, 5F-AKB48 is notably prone to inducing feelings of anxiety and paranoia. Individuals predisposed to these mental states should avoid its consumption.

Emotion Enhancement

Users may experience heightened emotional sensitivity and intensity under the influence of 5F-AKB48.

Thought Connectivity and Deceleration

This compound can influence thought processes, fostering both enhanced connectivity between ideas and a deceleration of thought speed.

Conceptual Thinking and Mindfulness

5F-AKB48 may facilitate conceptual thinking and promote mindfulness, potentially leading to deeper introspection and awareness.

Analysis Suppression and Dream Suppression

Users may perceive a suppression of analytical thinking while under the influence of 5F-AKB48. Additionally, the compound may impact dream activity, potentially suppressing dream recall or vividness.

Psychosis

Prolonged usage of synthetic cannabinoids like 5F-AKB48 may elevate the risk of psychosis, particularly among vulnerable individuals with predisposing factors for psychotic disorders, such as a personal or family history of schizophrenia.

Increased Music Appreciation and Auditory Effects

Some users report heightened appreciation for music and alterations in auditory perception while under the influence of 5F-AKB48.

Enhancements

Various cognitive enhancements may occur, though the specifics can vary widely among individuals and contexts.

Understanding 5F-AKB48: Toxicity and Harm Potential

Lack of Scientific Study

The toxicity and long-term health effects of recreational 5F-AKB48 use remain largely unstudied in scientific contexts due to its limited history of human usage. Consequently, the precise toxic dosage and potential long-term health implications remain unknown.

Anecdotal Evidence

Anecdotal reports from individuals within the community who have experimented with 5F-AKB48 suggest that at low to moderate doses used sparingly, there are generally no immediate negative health effects. However, caution is warranted, as overdose can lead to physical discomfort, including heart palpitations, vertigo, and sedation, even at doses lower than potentially dangerous levels. Overdose may also induce significant anxiety or result in the user falling asleep.

Mental Health Risks

Individuals with severe pre-existing mental conditions are advised against ingesting substances like 5F-AKB48 due to their propensity to intensify one's current state of mind and emotions. Prolonged usage of synthetic cannabinoids, including 5F-AKB48, may also heighten the risk of mental illness and psychosis, particularly among vulnerable individuals with predisposing factors such as a personal or family history of schizophrenia.

Tolerance, Addiction, and Withdrawal

Chronic use of 5F-AKB48 can lead to moderate addiction potential and psychological dependence in certain users. Tolerance to its effects develops with prolonged and repeated use, necessitating increasingly larger doses to achieve the same effects. Withdrawal symptoms and cravings may occur upon cessation of use.

Dangerous Interactions

Combining 5F-AKB48 with certain substances can pose significant risks, potentially resulting in dangerous or life-threatening outcomes. Users are advised to conduct thorough research to ensure the safety of combining substances. Some substances known to interact dangerously with 5F-AKB48 include stimulants like amphetamines and cocaine, as well as psychedelic compounds like LSD and DMT.

Legal Status

Global Regulations

• Brazil: Illegal, listed on Portaria SVS/MS nº 344.
• China: Controlled substance since October 2015.
• Czech Republic: Banned.
• Germany: Controlled under Anlage II BtMG (Narcotics Act, Schedule II) since July 17, 2013.
• Latvia: Schedule I drug.
• Switzerland: Controlled substance under Verzeichnis D.
• United Kingdom: Class B controlled substance.
• United States: Schedule I substance.
• Italy: Schedule I controlled substance.

Frequently Asked Questions (FAQ)

1. What is 5F-AKB48?

   • A synthetic cannabinoid substance belonging to the indazolecarboxamide class.

2. How does 5F-AKB48 affect the body?

   • It acts as an agonist for the CB1 and CB2 cannabinoid receptors, leading to various physical and cognitive effects.

3. What are the subjective effects of 5F-AKB48?

   • They include sensations such as a body high, changes in motor control, appetite enhancement, pain relief, alterations in perception, and emotional enhancement.

4. Is 5F-AKB48 safe to use?

   • The long-term health effects and toxicity of 5F-AKB48 have not been extensively studied. Anecdotal evidence suggests potential risks, particularly regarding mental health.

5. Can 5F-AKB48 lead to addiction?

   • Yes, chronic use of synthetic cannabinoids like 5F-AKB48 can lead to psychological dependence and addiction.

6. What precautions should be taken when using 5F-AKB48?

   • It's important to use harm reduction practices, dose cautiously, and avoid combining it with other substances, which can lead to dangerous interactions.

7. What is the legal status of 5F-AKB48?

   • Legal status varies by country, with many nations classifying it as a controlled substance due to its psychoactive properties.

8. Where can I find more information about 5F-AKB48?

   • Further research can be conducted through scientific literature, online forums, and harm reduction organizations.