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Table of Contents

1. Introduction to Methallylescaline
2. Chemistry of Methallylescaline
3. Pharmacological Insights
4. Dosage Guidelines
5. Physical Effects
6. Visual Effects
7. Cognitive Effects
8. Tolerance and Addiction Potential
9. Legal Status
10. FAQ (Frequently Asked Questions)

Exploring Methallylescaline: A Synthetic Phenethylamine Psychedelic

Introduction to Methallylescaline

4-Methallyloxy-3,5-dimethoxyphenethylamine, commonly referred to as methallylescaline or MAL, stands as a member of the synthetic psychedelic realm within the phenethylamine chemical class. This compound is recognized for its capacity to induce hallucinogenic and stimulant effects, akin to other mescaline analogs such as allylescaline, proscaline, and escaline.

Origin and Notable Mentions

The pioneering exploration into the effects of methallylescaline was undertaken by Alexander Shulgin, a prominent figure in the realm of psychedelic research. Shulgin documented his findings in his seminal work "PiHKAL: A Chemical Love Story." Within this literary piece, he delineates the dosage range for methallylescaline, advocating for oral consumption within the spectrum of 40mg to 60mg. Moreover, he elucidates that the duration of methallylescaline's action spans between 8 to 12 hours [1].

Understanding Effects and Risks

Anecdotal narratives often liken the effects of methallylescaline to those of mescaline, the renowned natural psychedelic compound found in various cacti species. However, it's noted that higher doses of methallylescaline may elicit a pronounced bodily sensation, commonly referred to as a "body load."

Pharmacological Insights and Safety Considerations

Despite its intriguing effects, methallylescaline remains enigmatic in terms of its pharmacological properties, metabolic pathways, and potential toxicity. Moreover, owing to its limited history of human usage, comprehensive data regarding its safety profile is sparse. Thus, it is paramount for individuals contemplating the use of methallylescaline to adhere to harm reduction practices and exercise caution in their exploration of this substance.

Understanding Methallylescaline: A Chemical Perspective

Chemistry of Methallylescaline

Methallylescaline, scientifically termed as 4-methallyloxy-3,5-dimethoxyphenethylamine, belongs to the substituted phenethylamine family. Its molecular structure entails a phenyl ring linked to an amino (NH2) group via an ethyl chain. Notably, methallylescaline is characterized by the presence of two methoxy functional groups (CH3O-) attached to carbons R3 and R5 of the phenyl ring.

At position R4, methallylescaline showcases a distinct substitution with a methallyloxy chain. This chain, comprising three carbon atoms, features an R2 methyl-substituted allyl group culminating in a double bond at the terminal carbon. An ether (oxygen) bridge facilitates the connection of this chain to the phenyl ring at R4.

Pharmacological Insights

Methallylescaline is presumed to function as a partial agonist at the 5-HT2A receptors, a subtype of serotonin receptors. These interactions are thought to underpin the psychedelic effects elicited by methallylescaline. However, the precise mechanisms governing these interactions and their manifestation in the psychedelic experience remain poorly understood.

Subjective Effects and Considerations

Disclaimer: The following section draws from the Subjective Effect Index (SEI), a compendium of anecdotal user reports and analyses by PsychonautWiki contributors. While informative, these effects should be approached with caution and skepticism.

The subjective effects of methallylescaline are still under exploration and development within the SEI framework. It's essential to acknowledge that these effects may not manifest predictably or consistently, with higher doses potentially yielding a broader spectrum of experiences. Additionally, the escalation of dosage heightens the risk of adverse effects, encompassing addiction, severe injury, or even fatality.

Deciphering Methallylescaline Dosage: Guidelines and Ranges

Threshold Dosage

For individuals seeking to discern the initial effects of methallylescaline, a threshold dosage of 5 mg is recommended.

Light Dosage

To experience mild effects without delving too deeply into the psychedelic realm, a light dosage of methallylescaline typically ranges between 15 to 25 mg.

Common Dosage

The common dosage range for methallylescaline spans between 25 to 40 mg. Within this range, users may encounter more pronounced effects while maintaining a manageable experience.

Strong Dosage

Venturing into the realm of strong effects necessitates a dosage of 40 to 60 mg of methallylescaline. At this level, the intensity of the experience may significantly escalate.

Heavy Dosage

Individuals seeking a profound and potentially overwhelming psychedelic journey may opt for a heavy dosage of 60 mg or more. This dosage threshold carries the potential for profound alterations in perception and consciousness.

Delving into Methallylescaline Effects: Physical, Visual, and Cognitive Insights

Physical Effects

• Stimulation: Methallylescaline typically induces a notable surge in physical energy levels, encouraging activities such as running, walking, climbing, or dancing. This energetic boost distinguishes it from other psychedelics like psilocin, which tend to induce sedation.
• Spontaneous Bodily Sensations: Users commonly report a range of intense bodily sensations, including a warm, euphoric glow reminiscent of MDMA, a sharp, electric tingling akin to mescaline, and an energetic pins-and-needles sensation similar to 2C-I.
• Perception of Bodily Lightness
• Physical Euphoria: Methallylescaline is noted for its physically euphoric effects, akin to other phenethylamines like MDA.
• Nausea: Moderate to high doses may lead to nausea, which can subside either after vomiting or as the peak effects set in.
• Muscle Cramp: Occasional muscle cramps may occur, especially in cases of malnourishment, dehydration, or strenuous activity.
• Tactile Enhancement: Users often report heightened tactile sensations, sometimes reaching an intense awareness of nerve endings.
• Appetite Suppression
• Frequent Urination
• Increased Heart Rate
• Increased Libido
• Muscle Contractions
• Pupil Dilation
• Excessive Yawning

Visual Effects

• Enhancements: Methallylescaline may intensify perception in various visual aspects, including color, pattern recognition, and visual acuity.
• Distortions: Users may experience visual distortions such as drifting, color shifting, depth perception alterations, perspective distortions, and symmetrical texture repetition.
• Symptoms: Tracers, afterimages, brightness alteration, diffraction, and geometric patterns similar to those seen in ayahuasca, psilocin, LSD, 2C-B, and 2C-I.
• Geometry: Visual geometry on methallylescaline is often described as organic, intricate, and fast-moving, with a variable size and multicolored scheme.
• Hallucinatory States: Internal hallucinations, including autonomous entities, settings, sceneries, and landscapes, may manifest, contributing to the overall visual experience.

Cognitive Effects

• Conceptual Thinking
• Cognitive Euphoria
• Delusion
• Emotion Enhancement
• Immersion Enhancement
• Increased Music Appreciation
• Memory Suppression
• Ego Death
• Novelty Enhancement
• Personal Bias Suppression
• Thought Acceleration
• Thought Loops
• Time Distortion

Tolerance and Addiction Potential

Methallylescaline is generally not habit-forming, and its use may lead to decreased desire over time. Tolerance builds rapidly after ingestion and diminishes within a week, with cross-tolerance observed among psychedelics.

Legal Status

• Canada: Not listed under the Controlled Drugs and Substances Act.
• Germany: Controlled under the NpSG.
• Switzerland: Named as a controlled substance under Verzeichnis E.
• United Kingdom: Illegal under the Psychoactive Substance Act.
• United States: Unscheduled but may be considered an analogue of mescaline under the Federal Analogue Act.

FAQ (Frequently Asked Questions)

1. What is methallylescaline?

• Methallylescaline is a synthetic psychedelic substance belonging to the phenethylamine chemical class, known for its hallucinogenic and stimulant effects.

2. What are the typical dosage ranges for methallylescaline?

• Threshold: 5 mg
• Light: 15 - 25 mg
• Common: 25 - 40 mg
• Strong: 40 - 60 mg
• Heavy: 60 mg +

3. What are the physical effects of methallylescaline?

• Physical effects may include stimulation, bodily sensations, euphoria, nausea, muscle cramps, enhanced tactile sensations, increased heart rate, and pupil dilation, among others.

4. What visual effects can be expected from methallylescaline?

• Visual effects may include enhancements in perception, distortions such as drifting and color shifting, geometric patterns, and hallucinatory states.

5. What cognitive effects are associated with methallylescaline use?

• Cognitive effects may include conceptual thinking, euphoria, delusions, emotion enhancement, memory suppression, ego death, and time distortion, among others.

6. Is methallylescaline addictive?

• Methallylescaline is not considered habit-forming, and tolerance to its effects develops rapidly with use.

7. What is the legal status of methallylescaline?

• The legal status varies by country, with some nations having specific regulations regarding its production, distribution, and possession. It's important to research local laws before obtaining or using methallylescaline.